A clinical study to evaluate heat and moisture exchangers and breathing system filters that are intended to replace the normal warming, humidifying and filtering functions of the upper airways when these structures are bypassed during anaesthesia and intensive care.

A prospective study to assess the safety and efficacy of Heat and Moisture Exchange filters and humidifiers in Mechanically Ventilated Patients. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/01/079199

Enrollment

Registered

2025-01-22

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J98- Other respiratory disorders Health Condition 2: Z930- Tracheostomy status

Interventions

Intervention1: Heat and Moisture Exchange filters and humidifiers: Heat and Moisture Exchangers (HME) are intended to replace the normal warming and humidifying the upper airways of tracheal-intubated

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1)Adults (â?¥18 years) requiring mechanical ventilation for â?¥24 hours. 2)Informed consent from the Legally Authorized Representative (LAR).

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1)Significant pre-existing lung disease.

Design outcomes

Primary

Measure	Time frame
Airway humidity levels as measured by digital psychrometry.Timepoint: The total duration of the study:3 months Time taken for each subject (if it involves interviews, follow up period):There is no follow-up involved in this study	—

Secondary

Measure	Time frame
1.Incidence of device-related adverse events. 2.Changes in ventilatory parameters, including peak airway pressures. 3.Occurrence of ventilator-associated pneumonia (VAP). Timepoint: The total duration of the study:3 months Time taken for each subject (if it involves interviews, follow up period):There is no follow-up involved in this study	—

Countries

India

Contacts

Public ContactDr Mathangi Krishnakumar

St Johnâ??s Medical College Hospital

mathangidoc@outlook.com919764062212

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026