Health Condition 1: A499- Bacterial infection, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
All India Institute of Medical Sciences, Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged more than 18 years and less than 60 years. Patients with suspected sepsis or septic shock exhibiting two or more of the following signs during their first 24 hours in the ICU: temperature more than 38 degree C, heart rate more than 90 beats per min, respiratory rate more than 20 breathsper min with partial pressure of arterial carbon dioxide less than 32 mmHg, and white blood cell count more than 12,000 cells per mm3.
Exclusion criteria
Exclusion criteria: Age less than 18 years Patients with terminal stage of disease (malignant cancer of any type, acquired immunodeficiency syndrome, end-stage liver or renal disease). On long term steroids/ Immunosuppressants/ Chemotherapy Neutropenic patients Patients with HIV Patients who were expected to have a short-term (less than 72 hours) intensive care treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to compare the prognostic value of suPAR vs Procalcitonin in patients with sepsis and septic shockTimepoint: During admission to the ICU (prior to therapeutic interventions) as well as in the morning of Day 7 after admission. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To define an optimum cut-off value of suPAR for diagnosing sepsis and predicting mortality. 2. To compare the the diagnostic accuracy of suPAR with procalcitonin for diagnosis of sepsis and septic shock in critically ill patients. 3. To observe an association between suPAR and duration of ICU stay, ventilator days, dialysis days. Timepoint: During admission to the ICU (prior to therapeutic interventions) as well as in the morning of Day 7 after admission. | — |
Countries
India
Contacts
Public ContactDr Revathi Abarna P K
AIIMS Jodhpur
Outcome results
None listed