To study a minimally invasive surgical treatment for Keratoconus and its impact on improvement of vision

Visual and Topographic Outcomes of Corneal Allogenic Ring Segments in Keratoconus - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079133

Enrollment

Registered

2025-01-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Corneal Allogenic Intrastromal Ring Segments (CAIRS) and Collagen Cross linking (C3R): Corneal Allogenic Intrastromal Ring Segments are small curvilinear segments which are trephined fr

Eligibility

Inclusion criteria

Inclusion criteria: Grade 1 to 4 Keratoconus patients (Amsler Krumeich grading) showing progression with sufficient minimum pachymetry

Exclusion criteria

Exclusion criteria: Autoimmune and immunodeficiency syndromes Previous viral keratitis Thin cornea less than 350 micrometers

Design outcomes

Primary

Measure	Time frame
Improvement in UCVA by range of â?¥ 2 lines Improvement in BCVA by â?¥ 1 line Decrease in spherical and astigmatic error Decrease in keratometryTimepoint: Follow up at 1 week, 1 month, 3 months, 6 months and 1 year.	—

Secondary

Measure	Time frame
Incidence of inflammatory keratitis Over correction or Under Correction of Refractive error Adverse events â?? Infection increased stromal haze ( when combined with Collagen cross linking)Timepoint: Follow up at 1 week, 1 month, 3 months, 6 months and 1 year.	—

Countries

India

Contacts

Public ContactDr Shivohn Annalie da Silva

Sankara Eye Hospital, Coimbatore

jkreddy@yahoo.com9443047456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026