None listed
Conditions
Interventions
Intervention1: Intravenous 5HT3 agents in Spinal Anarsthesia surgery: Group1: patients will receive ondansetron 8mg 30 minutes before spinal anaesthesia
Control Intervention1: Efficacy of two differen
Sponsors
Dr Sapna Bansal, Head of Department, Department of Anaesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: Patients of Age between 18-60years. American Society of Anaesthesiologist (ASA) physical status1-2. Patient scheduled for elective lower limb surgeries under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Patient with failed spinal Patient with allergy to 5HT3 receptor antagonist drugs Patients with coagulopathy PT/INR less than 1.5 or platelet count more than 1 lac per microlitre Patient who need a blood transfusion Prolonged surgical time led to the conversion of spinal anaesthesia to general anaesthesia Refusal of consent for spinal anaesthesia Patient with Parkinson’s disease Patient with dysautonomia Patients having any dysrhythmias and prolong QTc in preoperative ECG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of prophylactic ondansetron and palonosetron in reducing the incidence and severity of post spinal shiveringTimepoint: Intraoperative period after spinal anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| To study hemodynamic changes and adverse effects, if any. Timepoint: Intraoperative period after spinal anaesthesia | — |
Countries
India
Contacts
Public ContactSapna Bansal
MM institute of Medical Sciences and Research,Mullana,Ambala
Outcome results
None listed