Health Condition 1: K769- Liver disease, unspecified
Conditions
Interventions
Intervention1: High protein Group: High protein diet of 25% would be given to patients with MAFLD for a period of three months. Main sources of protein would be pulses,diary,legumes.
Control Intervent
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: 1.Newly diagnosed treatment naive consenting adults with MAFLD (controlled attenuation parameter; CAP more than 250. 2. Age 18-65 years
Exclusion criteria
Exclusion criteria: 1.Lean (BMI less than 23) 2.Individuals who had been hospitalized with complications of Diabetes mellitus, Chronic Kidney disease, Hypertension in the previous 6 months 3.Patients with viral hepatitis 4.Patients with significant alcohol consumption (regular consumption more than 10g per day for females and more than 20g/d in males), 5.Patients having chronic inflammatory bowel disease or any chronic and autoimmune diseases will be excluded 6.Pregnant & lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in Hepatic SteatosisTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Changes in systemic bioenergetics 2.Changes in cellular bioenergetics 3.Changes in metabolic features 4.Change in muscle massTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Jaya Benjamin
Institute of Liver and Biliary Sciences
Outcome results
None listed