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Comparing of Clonidine and Dexmedetomidine for Spinal Anesthesia in Lower Abdominal Surgery patients

Comparative evaluation of Dexmedetomine and Clonidine as an adjuvant to Ropivacaine (H) in subarachnoid block for infraumbilical surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079087
Enrollment
60
Registered
2025-01-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 3.4 ml of 0.5% ropivacaine (heavy) and 10 mcg of dexmedetomidine. Control Intervention1: Clonidine: 3.4ml of 0.5% ropivacaine(heavy) and 30mcg of clonidine

Sponsors

Datta Meghe Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.) Adult patients between the ages of 18 and 60 years, 2.) Patients scheduled for elective infra-umbilical surgeries, 3.) American Society of Anesthesiologists (ASA) physical status I or II, 4.) Surgery duration ranging between one and three hours.

Exclusion criteria

Exclusion criteria: 1.) Allergic reactions to any of the research drugs. 2.) Recognized contraindications to spinal anesthesia, 3.) Significant cardiovascular disease or a history of cardiac arrhythmias, 4.) Pregnant females, 5.) Coagulopathy or hemorrhagic conditions, 6.) Surgery duration less than one hour or more than three hours 7.) Incapacity to give informed consent.

Design outcomes

Primary

MeasureTime frame
Onset of sensory and motor blockade The level of sedation Hemodynamic parameters Timepoint: 24 hours

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Jayashree Sen

Datta Meghe Institute Of Higher Education And Research

jayashree_sen@rediffmail.com9813061192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026