Impact of Pain killer injection solutions used during root canal treatment on pain after treatment.

Effect of Four Different Irrigants as a Final Rinse on Post Operative Pain Following Single Sitting Root Canal Treatment in Symptomatic Irreversible Pulpitis: A Randomised Control Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079081

Enrollment

Registered

2025-01-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A00-B99- Certain infectious and parasitic diseases Health Condition 2: K040- Pulpitis

Interventions

Intervention1: Dexamethasone: Patients receiving Dexamethasone solution as irrigant and final rinse prior to obturation during the single visit Root canal Treatment. Duration of the interventions wil

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy patients aged between 18-60 years. 2.Permanent mandibular single rooted teeth with complete root formation. 3.Permanent mandibular single rooted teeth with diagnosis of symptomatic irreversible pulpitis

Exclusion criteria

Exclusion criteria: 1.Patients who are medically compromised. 2.Patients who had taken antibiotics in last 1 month and non-steroidal anti-inflammatory drugs 24 hours prior to procedure. 3.Patients contraindicated for Diclofenac Sodium, Ketorolac Tromethamine, Lignocaine, use of apex locator 4.Patients allergic to latex 5.Patients who are denied consumption of steroids due various reasons. 6.Patients who have renal and hepatic disorder 7.Patients with loss of tooth structure such that a rubber dam cannot be applied. 8.Pregnant and lactating women. 9.Adjacent carious teeth which are suspected of pulpal involvement. 10.Immature teeth or teeth with root resorption. 11.Teeth with calcified canals. 12.Teeth with sinus opening or periapical radiolucency with PAI score of 3 or higher.

Design outcomes

Primary

Measure	Time frame
Post Operative PainTimepoint: 6 hours, 24 hours, 48 hours, 72 hours	—

Secondary

Measure	Time frame
Post Operative Analgesic ConsumptionTimepoint: 6 hours, 24 hours, 48 hours, 72 hours	—

Countries

India

Contacts

Public ContactDr Sadhana Raina

Government Dental College and Hospital Nagpur

drsadhanaraina@gmail.com9423685967

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026