TO STUDY THE EFFECT OF PAIN USING KETAMINE IN PATIENTS UNDERGOING ELECTIVE SURGERIES.

PREEMPTIVE ANALGESIA USING LOW DOSE INTRAVENOUS KETAMINE FOR POST OPERATIVE PAIN IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079043

Enrollment

190

Registered

2025-01-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection Ketamine: In one group intravenous ketamine 0.5mg/kg given after after induction of general anesthesia and 10 minutes before surgical incision Control Intervention1: Normal Sa

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age : 18-60years. 2.ASA grade 1 and 2. 3.Patient posted for elective laparoscopic cholecystectomy. 4.Patients giving consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patient not willing to give informed and written consent. 2. BMI more than 40. 3. Surgery converted to open cholecystectomy. 4. Chronic pain syndrome. 5. Drugs , opiods , or any substance abuse. 6. History of allergy to ketamine. 7. Raised intra-cranial pressure. 8. Known case of hypertension , hyperthyroidism , psychiatric disorder. 9. History of seizure or taking anticonvulsant medication.

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of preemptive use of small dose intravenous ketamine on post operative pain using Numeric Rating Scale Score on patients undergoing elective laparoscopic cholecystectomyTimepoint: To evaluate the efficacy of preemptive use of small dose intravenous ketamine on post operative pain using Numeric Rating Scale Score at time 0(immediately after arousal), 6,12 and 24 hours on patients undergoing elective laparoscopic cholecystectomy	—

Measure

Time frame

To evaluate the efficacy of preemptive use of small dose intravenous ketamine on post operative pain using Numeric Rating Scale Score on patients undergoing elective laparoscopic cholecystectomyTimepoint: To evaluate the efficacy of preemptive use of small dose intravenous ketamine on post operative pain using Numeric Rating Scale Score at time 0(immediately after arousal), 6,12 and 24 hours on patients undergoing elective laparoscopic cholecystectomy

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Secondary

Measure	Time frame
1. To evaluate time interval for first request of analgesia. 2.To evaluate post operative total opioid consumption in first 24 hours. 3. To evaluate the incidence of post operative side effects like nausea , vomiting, delirium and hallucination. Timepoint: To evaluate time interval for first request of analgesia, post operative total opioid consumption in first 24 hours and any post operative complications	—

Measure

Time frame

1. To evaluate time interval for first request of analgesia. 2.To evaluate post operative total opioid consumption in first 24 hours. 3. To evaluate the incidence of post operative side effects like nausea , vomiting, delirium and hallucination. Timepoint: To evaluate time interval for first request of analgesia, post operative total opioid consumption in first 24 hours and any post operative complications

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Countries

India

Contacts

Public ContactDr Nazia Akhtar Barbhuiya

Gauhati Medical College and Hospital , Guwahati

aldiona.shanpru1958@gmail.com9101813237

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026