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Cognitive Interventions in First Episode Psychosis-RCT

A Randomized Controlled Trial of cognitive interventions in Patients with First Episode Psychosis to improve cognitive outcomes. - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079027
Enrollment
300
Registered
2025-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

Intervention1: Cognitive Intervention: Domains: Attention, Working Memory (WM), Cognitive Flexibility (CF), Response Inhibition (RI), Memory (M) Social Cognition (SC). 12 weeks of cognitive intervent

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed with schizophrenia as per DSM-5 criteria5, with duration of illness less than 5 years Currently in clinical remission as defined by Andreasen et al 20056.

Exclusion criteria

Exclusion criteria: Patients who were not in clinical remission Those with comorbid organic brain syndrome or intellectual disability Those refuse to consent for the study

Design outcomes

Primary

MeasureTime frame
Equal to or more than for FOToM 0.98 SOToM 0.82 FPCI 0.91 SPI 0.89 SPI High Intensity 0.92 SPI Low Intensity 0.86 NSPI 0.93 NSPI High Intensity 0.94 NSPI Low Intensity 0.87 DF 10.04 DB 7.45 COWA Average New words 11.66 AVLT LTPR 93.45 Immediate Recall 13.33 Delayed Recall 13.41 Total Learning score 60 Interference 8.12 Hits 14.66 SPM IQ 122.12 Equal to or Less than for CTMT Part A 29.54 Part B 69 SCWT score 42.16 Misses 0.33 False Alarms 0.41 Timepoint: 12 weeks post intervention

Secondary

MeasureTime frame
Improvement in Level of functioning, disability and quality of life from baseline scoresTimepoint: 12 weeks post intervention

Countries

India

Contacts

Public ContactDr Swapnajeet Sahoo

Post Graduate Institute of Medical Education & Research, Chandigarh

swapnajit.same@gmail.com8872727744

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026