Skip to content

Comparison between two techniques of track embolization in prevention of post lung biopsy complications.

Comparison between Gelatine Sponge and Normal Saline as percutaneous lung biopsy tract embolization agents for prevention of post-biopsy complications: GELINE randomized controlled trial. - GELINE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079025
Enrollment
66
Registered
2025-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C30-C39- Malignant neoplasms of respiratory and intrathoracic organs

Interventions

Intervention1: Use of either Gelatine Sponge or Normal saline as percutaneous tract embolization agents post lung biopsy.: After the end of lung biopsy while withdrawing the needle there will be insti
in the third group, no tract embolization will be done and is kept as a control group. The rates of pneumothorax will be assessed in each group and used for comparison.

Sponsors

Aryan Manjhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients with lesions involving the lung parenchyma, with or without extra-pulmonary extension (including pleural/chest wall/ mediastinal extension) amenable to percutaneous CT-guided biopsy.

Exclusion criteria

Exclusion criteria: 1. Patient refusal for consent. 2. Lung lesions deemed not amenable to safe percutaneous image-guided biopsy. 3. Patients with un-correctable coagulopathy, shock, cardiac failure, respiratory failure, sepsis 4. Pre-procedure pneumothorax, pneumomediastinum, surgical emphysema. 5. Pneumothorax that is developing during the procedure and before the withdrawal of the coaxial needle. 6. Patients with bronchopleural fistula.

Design outcomes

Primary

MeasureTime frame
To see whether the use of tract embolization agents has any effect of reduction in the incidence of pneumothorax post lung biopsy.Timepoint: The presence of pneumothorax will be detected using HRCT chest planned immediately post-procedure and after two hours.

Secondary

MeasureTime frame
To assess the rates of incidence of other major and minor complications associated with lung biopsy in between the three groups of study and to see whether the use of tract embolization agents has any effects on the reduction of those complications. Timepoint: Intra as well as immediate post-procedural complications will be assessed clinically and on HRCT chest planned immediately post-procedure and after two hours. Follow-up for delayed complications will be done after a week.

Countries

India

Contacts

Public ContactDr Sameer Peer

AIIMS BATHINDA

sameer.peer602@gmail.com9797722727

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026