Evaluation of efficacy of Herbal, Chlorine dioxide and Probiotic based mouthwashes on reduction of biofilm in children of 6-12 years

Comparative evaluation of Herbal, Chlorine dioxide and Probiotic based mouthwashes on reduction of biofilm in 6-12 years old children: An Invivo study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/01/079024

Enrollment

Registered

2025-01-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis Health Condition 2: K029- Dental caries, unspecified

Interventions

Intervention1: Herbal mouthwash: Oral rinse with 10ml of mouthwash for 60 sec once daily for 14 days Intervention2: Chlorine dioxide mouthwash: Oral rinse with 10ml of mouthwash for 60 sec once daily

Eligibility

Inclusion criteria

Inclusion criteria: 1)Children within the age range of 6-12 years. 2)Children with DMFT score = 2 3)Children with no history of antibiotic or probiotics in any form in the past three months.

Exclusion criteria

Exclusion criteria: 1)Medically compromised children 2)Children with history of systemic allergies and diseases. 3)Children using any prosthodontic/orthodontic appliance.

Design outcomes

Primary

Measure	Time frame
Sillness and Loe Plaque IndexTimepoint: Pre evaluation(baseline plaque scores will be assessed) After 14 days of intervention, post evaluation of plaque scores will be assessed.	—

Secondary

Measure	Time frame
s.mutans bacterial loadTimepoint: pre evaluation(baseline s.mutans count on Day 0) & After 14 days of intervention, post evaluation of s.mutans count (Day 15)	—

Countries

India

Contacts

Public ContactDr Jayalakshmi Pandranki

Dr.NTR University of Health Sciences

mds.deepthi@gmail.com9912860194

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026