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The clinical trial to study the effect of two different materials on bone healing in patients undergoing endodontic surgery

Post Endodontic surgery bone healing comparison-Platelet Rich Fibrin and Bone Putty: A Randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/078984
Enrollment
44
Registered
2025-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K14- Diseases of oral cavity and salivary glands Health Condition 2: K04- Diseases of pulp and periapical tissues Health Condition 3: K048- Radicular cyst Health Condition 4: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Bone Putty: CBCT (3D) images of the region of interest will be taken, preoperatively. After an appropriate diagnosis, root canal treatment will be done as per protocol. During surgery,

Sponsors

All India Institute of Medical Sciences, Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients over the age of 16 years regardless of the gender. 2. Patients with large periapical lesions of endodontic origin. 3. Patients planned for surgical intervention subsequent to conventional endodontics.

Exclusion criteria

Exclusion criteria: 1. Patients not planned for endodontic surgery. 2. All patients for medical reason who cannot undergo endodontic surgery because of systemic conditions 3. Patient denied to participate

Design outcomes

Primary

MeasureTime frame
Extent of lesion will be calculated Supero-inferiorly, mesio-distally, bucco-lingually and assess the change in defect size and volume using CBCT volumetric analysis preoperatively and post operatively in one year of follow upTimepoint: Preoperatively and Post operatively (one year of follow up)

Secondary

MeasureTime frame
Amount of radiographic bone fill will be calculatedTimepoint: Pre operative and post operative (1 year of follow up)

Countries

India

Contacts

Public ContactDr Asna K A

All India Institute of Medical Sciences, Jodhpur

kumarpr@aiimsjodhpur.edu.in9818402220

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026