Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed cases of COPD. 2. Stage I, II and III COPD, clinically stable for at least 3 months. 3. Sufficient cognitive function to follow instructions for spirometry. 4. Able to walk without aid. 5. Willingness to undergo the prescribed modified lifestyle protocol of NPT 6. Provide informed consent.
Exclusion criteria
Exclusion criteria: Exclusion 1.Myocardial infarction within last 3 months 2.Asthma 3.Recent surgery of thorax, abdomen, head, eyes or ear. 4. Haemoptysis. 5.Severe hypertension (BP more than 200/120 mm Hg). 6.Recurrent angina within the previous six months. 7.Recent injury or neuromuscular conditions interfering with exercise tests. 8.Current Smokers. 9.Active Tuberculosis infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective Outcome Parameters: 1. The efficacy of the NPT regimen will be evaluated based on various objective measures, including vital signs such as blood pressure (BP), pulse rate (PR), respiratory rate (RR), and oxygen saturation (SpO2), as well as findings from chest examinations. 2. Pulmonary function tests, including forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio. We will assess lung functions using spirometry. 3. Laboratory investigations will monitor changes in complete blood count (CBC), liver function tests (LFT), kidney function tests (KFT), serum electrolyte levels, random blood sugar (RBS), high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), vitamin D levels, D-dimer, and lipid profile. In addition, the occurrence of respiratory infection will be evaluated to assess the impact of the intervention.Timepoint: 12 weeks objective Outcome Parameters | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective Outcome Parameters 1. Subjective outcomes will focus on the patients perception of their COPD symptoms and overall well-being. 2. Dyspnoea severity will be assessed using the Modified Medical Research Council (MMRC) Dyspnoea Scale. Health related quality of life will be measured using the St. Georges Respiratory Questionnaire (SGRQ) and the COPD Assessment Test (CAT).Timepoint: 12 wks;3. Mental health status will be evaluated using the WHO (Five) Well Being Index, while sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). These subjective measures will provide insights into the impact of the NPT regimen on symptom burden, functional status, mental health, and sleep disturbances experienced by COPD patients.Timepoint: 12 weeks | — |
Countries
India
Contacts
ESIC Medical College Hospital Faridabad