Health Condition 1: O048- (Induced) termination of pregnancywith other and unspecified complications
Conditions
Interventions
Intervention1: Tablet Letrozole: 10mg oral Letrozole for three days.
Control Intervention1: Placebo tablet: placebo tablet resembling Letrozole tablet for 3 days
Sponsors
Dr Murali S
Eligibility
Inclusion criteria
Inclusion criteria: 12 to 24 weeks MTP
Exclusion criteria
Exclusion criteria: Severe anemia, heart disease, bleeding disorders, Previous LSCS, liver or renal disorders, known allergy or contraindications to the study drugs (chronic systemic use of corticosteroids; chronic adrenal failure; current therapy with anticoagulants; or inherited porphyria) Low lying placenta, previous history of hysterotomy, Breast feeding, Intrauterine device in situ, multiple gestation and concurrent usage of any other ripening agent like cervical Foley s catheter placement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete expulsion (including fetus and placenta).Timepoint: 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare induction-abortion interval, hospital stay, misoprostol dosage, need for surgical evacuation, side effects and acceptability of the two regimen in women undergoing termination of second trimester pregnancy.Timepoint: 24 h after misoprostol adminstration, Time of discharge. | — |
Countries
India
Contacts
Public ContactS Murali
Jawaharlal institute of postgraduate medical education and research
Outcome results
None listed