Health Condition 1: K746- Other and unspecified cirrhosis ofliver Health Condition 2: K703- Alcoholic cirrhosis of liver
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients over 18years of age undergoing adult living donor liver transplant from December 2022 to November 2023 will be enrolled in the study
Exclusion criteria
Exclusion criteria: - Patients less than 18years of age. - Patients with H/O recent (less than one week) Hepatorenal syndrome/Acute Kidney Injury - Patients with known H/O chronic kidney disease - Patients with Hepatopulmonary syndrome/Portopulmonary Hypertension - Combined procedure with liver transplant. - H/O hepatic encephalopathy (Grade 2 or more at the time of transplant) - Patients with acute liver failure. INTRAOPERATIVE- - Patients requiring intraoperative continuous renal replacement therapy - Patients with incomplete data POSTOPERATIVE - Patient requiring mechanical ventilation for graft dysfunction or neurological complications. - Patient requiring mechanical ventilation for renal replacement therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •Evaluate our rate of early extubation (on-table extubation, extubated within 4hours postoperatively) after living donor liver transplant, mean duration of mechanical ventilation, pulmonary complications such as pulmonary edema , pleural effusion requiring drainage within 72 hours postoperatively. •Incidence of Acute kidney injury within 72 hours postoperatively. Need for renal replacement therapy.Timepoint: 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative need for packed red blood cells, vasopressor requirement (noradrenaline-mcg/kg/min and total vasopressin units) and rate of vascular complications (hepatic artery thrombosis)Timepoint: Intraoperative period | — |
Countries
India
Contacts
BLK Max Superspeciality Hospital