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to evaluate between topical metformin 30 percent vs topical benzoyl peroxide 2.5 percent in acne vulgaris

Comparison of effectiveness of topical metformin 30 percent gel vs topical benzoyl peroxide 2.5 percent gel alone in acne vulgaris a randomized non inferiority open label study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/078918
Enrollment
96
Registered
2025-01-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Topical metformin 30 percent: It will be applied topically once daily for 8 weeks Control Intervention1: Topical benzoyl peroxide 2.5 percent: It will be applied topically once daily fo

Sponsors

IMS AND SUM HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All clinically diagnosed cases of acne vulgaris cases more than 18 years of age consenting for the study

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Patients who received any systemic/topical treatment within 1 month prior to enrollment. Patients with acne Tarda Nodulocystic acne Females on Oral Contraceptive pills H/O liver or Kidney dysfunction, diabetes Those with features of hyperandrogenism like hirsutism, irregular menses, FPHL. K/C/O PCOD

Design outcomes

Primary

MeasureTime frame
Compare the decrease in lesional count Timepoint: At baseline, 4 weeks, 8 weeks—

Secondary

MeasureTime frame
To assess the quality of lifeTimepoint: At baseline, 4 weeks, 8 weeks—

Countries

India

Contacts

Public ContactDr Bikash Ranjan Kar

IMS and SUM Hospital

karbikash@gmail.com9937428181

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026