None listed
Conditions
Interventions
Intervention1: Moisturizer and Retinol Serum: In the morning, subjects will be asked to wash their face with cleanser, apply moisture and sunscreen. In the evening, subjects will be asked to wash thei
Sponsors
MS Clinical Research Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female subjects aged between 20-40 years (both ages inclusive) 2. Subjects who have not used retinol-based products minimum 8 weeks prior to enrollment. 3. Subjects who only use base moisturizer for a minimum at least 4 weeks prior to enrollment. 4. Subjects with self-declared non-sensitive skin and as confirmed by modified Baumann’s questionnaire with score less than 24. 5. Subjects with roughness score of greater than or equal to 4 (0-9) measured by Dermatological Assessments. 6. Subjects with underneath eye wrinkles score of greater than or equal to 2 (grades 0-5) as per atlas measured by Dermatological Assessments. 7. Subjects with 1hour sebum secretion rate of more than 90 (oily skin) in each test group preferably in equal ratio. 8. Subjects with 1hour sebum secretion rate of less than 90 (non-oily skin) in each test group preferably in equal ratio. 9. Subjects with all skin types, preferably in equal ratio of normal, oily, dry and combination types as confirmed by general health screening form. 10. Subjects with Fitzpatrick phototype III, IV, V and VI as confirmed by general health screening form. 11. Subject free of excessive hair, cuts, abrasions, fissures, wounds, lacerations, or any other skin conditions on the face. 12. Subjects who agree not to use any other product or treatment or home remedy or except the provided products on their face during the study period. 13. Subjects who agree not to carry out bleaching or any other procedures including facial etc. on face during the study period. 14. Subjects who agree not to expose to excessive direct sun light (sun exposure not more than half an hour daily and during that time use of umbrella to cover face). 15. Subjects willing to give a voluntary written informed consent, photography re-lease and agree to come for regular follow-up. 16. Subjects willing to abide by and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1. Subjects who do not agree to abstain from other cosmetic products including colour cosmetics 2. Subjects who work outdoors and those with direct UV or sun exposure 3. Subjects with known skin conditions that may impact the assessment. 4. Subjects with any other signs of significant local irritation or skin disease. 5. Subjects currently taking any medication and/or taken medication within 30 days prior to the study, which the investigator believes may influence the interpretation of the data, such as but not limited to oral isotretinoin. 6. Subjects having clinically significant systemic or cutaneous disease, chronic illness or major surgery in the last year. 7. Subjects undergoing treatment of any skin condition on their face. 8. Subjects not willing to discontinue other topical facial products. 9. Subject who are allergic and/or have known sensitivity to any of the treatment products and or ingredients of the treatment products that will be provided. Subjects who have participated in a similar clinical study 4 weeks before this study. 10. Subjects who are pregnant and/or planning to get pregnant and/or nursing and/or planning to nurse (self-declared). 11. Subjects who are on any kind of supplements or taking nutraceuticals. 12. Subjects who are employees of the sponsor or the CRO.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in early signs of ageing after usage of a regimen containing retinol in comparison to baseline.Timepoint: Baseline, Week 1, Week 4, Week 8, 3 days after week 8. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement in early signs of ageing after using a regimen containing retinol in comparison to baseline. 2. Improvement in hydration and early signs of ageing after using the moisturizer in comparison to baseline 3. Dermatological tolerability of test products.Timepoint: Baseline, Week 1, Week 4, Week 8, 3 days after week 8. | — |
Countries
India
Contacts
Public ContactSudhanthiran S
MS Clinical Research
Outcome results
None listed