Skip to content

Clarification(s) with Reply Modification(s) A comparison of duration of spinal block in patients posted for elective lower abdomen and lower limb surgeries when the adjuvant is given intravenously, and local anesthetic is given in spine alone.

Intravenous Dexamethasone versus Intravenous Normal Saline in Prolonging the Effect of Spinal Anesthesia in Lower Abdominal and Lower Limb Surgeries Randomized Control Trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/078873
Enrollment
80
Registered
2025-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone: Patients will be administered intravenous dose of 8mg of dexamethasone immediately after the administration of spinal anesthesia with 3ml of hyperbaric ropivacaine 0.75%

Sponsors

Rohilkhand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologist (ASA) grade I or II and Patient having elective procedures on lower limbs and abdomen.

Exclusion criteria

Exclusion criteria: 1.Patient refusal for the procedure 2.Infection at the site 3.Any abnormality of spinal anatomy 4.Allergy or intolerance to regional anesthesia 5.Coagulopathy or Bleeding disorder

Design outcomes

Primary

MeasureTime frame
1. Onset of sensory & motor blockade 2. Highest level of sensory block 3. Time for two segment regression of sensory block 4. Duration of motor blockade 5. Time for first rescue analgesic 6. Incidence of post-operative nausea, vomiting and post spinal shivering.Timepoint: for sensory blockade the time to assess will be by pin prick sensation every 2min till loss at T06 dermatome and motor till the modified bromage grade 3 occurs. after the surgery, the time needed for the 1st rescue analgesia will be noted

Secondary

MeasureTime frame
Hemodynamic parameters (Heart rate, systolic and diastolic blood pressure, mean arterial pressure)Timepoint: During the surgery the patient’s pulse rate, Systolic and Diastolic blood pressure, Mean Arterial Pressure, arterial oxygen saturation will be recorded every 3 minutes for 30 minutes and then every 5 minutes until finishing the procedure. In post-operative period parameters will be recorded for every 15 minutes for 45 minutes and then hourly for 2 hours.

Countries

India

Contacts

Public ContactDr Richa Chandra

Rohilkhand medical college and hospital

sakshigupta737@gmail.com8920613842

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026