Evaluate the impact of hydrocortisone adjunct therapy on pao2/fio2 ratio in pneumonia patients compared to standard care alone

Evaluate the impact of hydrocortisone adjunct therapy on pao2/fio2 ratio in pneumonia patients compared to standard care alone. - Nil

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/078856

Enrollment

128

Registered

2025-01-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J189- Pneumonia, unspecified organism

Interventions

Intervention1: injectable hydrocortisone 200mg: injectable hydrocortisone 200mg given twice daily for 4 days and tapper for next 4 days along with standard care Control Intervention1: Standard treatm

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients age 18 years or more Patient is diagnosed case of Pneumonia requiring non-invasive ventilation or invasive mechanical ventilation pf ratio less than 300 and Chest radiograph showing lung involvement

Exclusion criteria

Exclusion criteria: refuse to give consent for study severe immunosuppression pregnancy A coexisting medical condition requiring steroid therapy A preexisting medical condition with the life expectancy less than 3months Any cancer patient on palliative care Patients with heart failure

Design outcomes

Primary

Measure	Time frame
change in PaO2/FiO2 ratio in both groups at 5 days after admission or at time of discharge whichever is earlierTimepoint: 5days	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Shweta

Dr. RMLIMS LUCKNOW

drsujeetrai@gmail.com9161758940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026