Effect of Vamana (Panchakarma therapy) and Kuberaksha Vati on hormonal profile of Polycystic ovarian syndrome (PCOS)Patients

A clinical trial to evaluate the efficacy of Vamana karma along with Kuberaksha vati on PCOS profile in the patients of Polycystic ovarian syndrome - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078810

Enrollment

Registered

2024-12-31

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E282- Polycystic ovarian syndrome

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients with any 2 or more clinical features of PCOS like- Amenorrhea or Oligomenorrhoea Clinical hyperandrogenism (acne, hirsutism) Polycystic Ovaries on USG. and Patients fit for Vamana Karma.

Exclusion criteria

Exclusion criteria: 1. Patients who are contraindicated for vamana karma such as kshatkshina, atishtula,atikrusha,bala,vriddha,durbala,shranta,pipasita . 2. Patients suffering from Pelvic diseases like Endometriosis, PID, Fibroid uterus. 3. Organic lesions of reproductive tract like tuberculosis, carcinoma and congenital deformities. 4. Patients with renal or hepatic impairment (Sr. creatinine more than 1.8mg/dl along with Sr. Urea more than 60 mg/dl, SGOT and SGPT more than Five times of upper limit . Patients having LDL and Triglycerides more than two times of upper limit. 5. Patients with co-morbid conditions such as Hypertension grade 2 (more than equal to 160/100mm of Hg) or more, Diabetes Mellitus (having HbA1c more than 7.5% with or without hyperglycemic medications.

Design outcomes

Primary

Measure	Time frame
The proportion of patients showing effect on PCOS Profile.Timepoint: Baseline,after vamana including sansarjana krama,Day 120.	—

Secondary

Measure	Time frame
1) The proportion of patients showing effect on status of menstruation (duration, interval, pain associated with menses), hirsutism, acne. 2) The proportion of patients showing effect on weight, BMI (body mass index), waist-hip ratio, lipid profile. 3)The proportion of patients showing effect on ovulation. Timepoint: Baseline,after vamana,after 1st menstrual cycle,after 2nd menstrual cycle,day 120. Follicular study will be done every 10th,12th, 14th, 16th, 18th day of cycle for 2 consecutive cycles.	—

Measure

Time frame

1) The proportion of patients showing effect on status of menstruation (duration, interval, pain associated with menses), hirsutism, acne. 2) The proportion of patients showing effect on weight, BMI (body mass index), waist-hip ratio, lipid profile. 3)The proportion of patients showing effect on ovulation. Timepoint: Baseline,after vamana,after 1st menstrual cycle,after 2nd menstrual cycle,day 120. Follicular study will be done every 10th,12th, 14th, 16th, 18th day of cycle for 2 consecutive cycles.

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Countries

India

Contacts

Public ContactAnjali Pradip Karande

Ayurvedic And Unani Tibbia College And Hospital Karol Bagh New Delhi

manojshamkuwar@gmail.com9354925019

Outcome results