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To see difference in temperature with two spinal drugs morphine and fentanyl in pregnant women undergoing cesarean section

Comparison of perioperative hypothermia with intrathecal morphine (ITM) vs intrathecal fentanyl (ITF)in parturients planned for caesarean section under spinal anaesthesia - nill

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078790
Enrollment
160
Registered
2024-12-31
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Intrathecal Morphine: Single shot hyperbaric Bupivacaine of 1.6ml of 0.5% (8 mg) along with 150 mcg morphine will be given intrathecally Control Intervention1: Intrathecal Fentanyl: Sin

Sponsors

Director of Postgraduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Parturients planned for elective caesarean section under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1.ASA Status = 3 2.Refusal to take part in study. 3.Core temperature less than 36.0 ? C degrees in the preoperative assessment. 4.Contraindications for spinal anaesthesia (any bleeding disorder or coagulation abnormality). 5.Patients with any allergy to study medication (Morphine, Fentanyl, Bupivacaine). 6.Patient taking medications which impact thermoregulation (vasodilators, Antipsychotics). 7.Twin pregnancy. 8.Conversion of spinal anaesthesia to GA.

Design outcomes

Primary

MeasureTime frame
incidence of hypothermia in the two groupsTimepoint: 0,15,30,45,60,75,90,105,120 minutes of spinal anesthesia 0,30,60,90,120 min post surgery 3,4,5,6,7,8,9,10,11,12 hours post surgery

Secondary

MeasureTime frame
1. Incidence of shivering 2. Duration of maximum temperature fall following intrathecal morphine and intrathecal fentanyl 3. Total duration of hypothermia 4. Incidence of respiratory depression, pruritus, PONV, urinary retentionTimepoint: Post spinal anesthesia till 24 hours

Countries

India

Contacts

Public ContactDr Prerna Varma

Post Graduate Institute of Medical Education and Research

prerna.varma@gmail.com9654238627

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026