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Easing TMJ Pain Comparing Two Approaches to Treatment

To evaluate the efficacy of Intra-articular injectable platelet-rich fibrin with arthrocentesis versus arthrocentesis alone in the management of temporomandibular joint internal derangement: A Prospective Study - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078787
Enrollment
40
Registered
2024-12-31
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M266- Temporomandibular joint disorders

Interventions

Intervention1: Arthrocentesis with Ringer lactate: Dose-150-200ml Ringer Lactate Frequency - Total 3 injection , each session single injection at 0,2,4week. Route of administration- Intra-articular i

Sponsors

Government College of Dentistry Indore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. The study included patient aged 18-55 years. suffering from TMJ internal derangement with reduction and patient who have given consent. 2. All the patients whose condition was refractory to conservative treatment were included in the study.

Exclusion criteria

Exclusion criteria: 1) Patients suffering from TMJ related Disorder other than Internal derangement. 2) Patients maintained on anti-coagulants, muscle relaxants, non-steroidal anti-inflammatory drugs within 48 h preoperatively, corticosteroid injection at treatment site within one month or systemic use of corticosteroids within 2 weeks was also excluded in this study. 3) Patients who were pregnant or in the lactation period. 4) Patients who were edentulous were excluded

Design outcomes

Primary

MeasureTime frame
to evaluate the efficacy of arthrocentesis with and without i-PRF injection in upper joint space on the improvement of symptoms and jaw function in management of TMJ internal derangement.Timepoint: Baseline 1 week 1 month 2 months 3 months 6 months

Secondary

MeasureTime frame
1) To compare preoperative and postoperative pain in TMJ using Visual analogue scale. 2)To compare maximum mouth opening both pre and post operatively. 3)To compare clicking sound pre and postoperatively. 4)To compare the lateral Jaw MovementTimepoint: Baseline 1 week 1 month 2 months 3 months 6 months

Countries

India

Contacts

Public ContactDr. Sachin Jha

Government College Of Dentistry Indore

vilasnewaskar@yahoo.com9827028864

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026