Comparison of local anesthesia onset and duration based on temperature and pharmacological agents

Comparative evaluation of the efficacy of supplemental local anesthesia using temperature variation along with pharmacological agents for irreversible pulpitis: a randomized controlled trial - LA

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078736

Enrollment

120

Registered

2024-12-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: 1ml of warm 2%lignocaine: check the onset and duration of supplemental local infiltration along with main nerve block Intervention2: 1ml of cold 2% lignocaine with 1:200000 adrenaline:

Eligibility

Inclusion criteria

Inclusion criteria: Teeth with symptomatic irreversible pulpitis Teeth with normal tooth anatomy Class I or II medical history (American Society of Anesthesiologists)

Exclusion criteria

Exclusion criteria: Allergic to local anesthesia Periodontally compromised teeth. Teeth with vertical fracture

Design outcomes

Primary

Measure	Time frame
effect of various agents as supplemental anesthesia on onset and duration of anesthesia for patients with symptomatic irreversible pulpitisTimepoint: 3 minutes after injection local infiltration before starting treatment and during the procedure	—

Secondary

Measure	Time frame
any associated side effectTimepoint: duration of supplemental local anesthesia;patient pain levels assessed before & after the procedure using numeric pain rating scaleTimepoint: pain rating scale before & after the completion of procedure	—

Countries

India

Contacts

Public ContactAakash Gupta

AIIMS, Bathinda

drtarunkumarsingh@gmail.com9560627466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026