A comparative study of addition of an adjunct to local anesthetic versus local anesthetic alone in ultrasound guided nerve group block for proximal lower limb fractures near the hip joint.

Dexmedetomidine and Bupivacaine versus Bupivacaine Alone in Ultrasound Guided PENG block in proximal Femoral Fractures: a Randomized Comparative study - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078728

Enrollment

Registered

2024-12-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S720- Fracture of head and neck of femur

Interventions

Intervention1: Dexmedetomidine and Bupivacaine Combination: patients will receive 50mcg (0.5ml) dexmedetomidine in PENG block with 20 ml of .25% bupivacaine, before giving spinal anesthesia Control

Eligibility

Inclusion criteria

Inclusion criteria: criteria:ASA 1,2,3 patients of 18 to 60 years of age with only proximal femur fractures (neck of femur, intertrochanteric, and subtrochanteric fractures) undergoing surgery under spinal anaesthesia, having significant pain visual analogue scale (VAS) =4 and expected surgery duration of less than 150 min

Exclusion criteria

Exclusion criteria: Patients with old fractures (more than 7 days), polytrauma, bleeding disorders or coagulopathy, local site infection, difficulty expressing pain scores such as hearing disability, mentally challenged, dementia or psychiatric illness,patients on chronic opioids or drug addicts.

Design outcomes

Primary

Measure	Time frame
Duration of analgesiaTimepoint: FIRST 24HOURS	—

Secondary

Measure	Time frame
Ease of spinal position score (EOSP)Timepoint: 30 minutes after the block;Postoperative pain scoresTimepoint: at .5h,2h, 4h,6h,12h,24h;Quadriceps weaknessTimepoint: At 6 hours postoperatively;Total number of rescue analgesics in first 24 hoursTimepoint: 24 hours;Postoperative inflammatory stress responseTimepoint: Preoperative,1 hour postoperatively;Side effects ,if anyTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactRuchi singh

Government institute of medical sciences

Instantruchi@gmail.com9165291956

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026