Implant with membrane for better bone formation

Comparative evaluation of A-prf+ or collagen membrane on hard and soft tissue changes following immediate implant placement- A randomised clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078666

Enrollment

Registered

2024-12-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K039- Disease of hard tissues of teeth,unspecified

Interventions

Intervention1: COLLAGEN MEMBRANE: Collagen membrane will be placed to augment soft tissue at the implant site. Membrane extends 2-3mm under the buccal and lingual aspect of the alveolar ridge and secu

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects aged between 18- 60 years. 2. Patient with adequate oral hygiene status. 3. No active periodontal disease. 4. Patients requiring the replacement of one or more non-restorable teeth with sufficient bone volume will be selected for the study. 5. Patient willing to give informed consent. 6. Patients with good compliance so as to meet the follow-up.

Exclusion criteria

Exclusion criteria: 1. Patient with systemic disease. 2. Patient with autoimmune disease, psychiatric disorder , osteoporosis. 3. Patient undergoing or who underwent radiation therapy and chemotherapy to the head and neck region during the last 12 months. 4. Patient with poor oral hygiene. 5. Alcoholics , drug abusers or heavy smokers. 6. Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
1. SOFT TISSUE THICKNESS Midbuccal and Midlingual/Midpalatal soft tissue thickness will be measured 3mm from the gingival crest margin using endodontic K-File with stopper. Standardization achieved using indented acrylic stent. The soft tissue thickness on endodontic K-file will be measured using digital vernier caliper. 2. WIDTH OF KERATINIZED TISSUE will be measured using UNC 15 periodontal probe, using a standardized acrylic stent. 3. RADIOGRAPHIC PARAMETERS Crestal bone levels will be measured with CBCT using acrylic stent with gutta percha point for standardization before implant placement (baseline) and after 3 months postoperatively.Timepoint: Baseline to 3 months	—

Measure

Time frame

1. SOFT TISSUE THICKNESS Midbuccal and Midlingual/Midpalatal soft tissue thickness will be measured 3mm from the gingival crest margin using endodontic K-File with stopper. Standardization achieved using indented acrylic stent. The soft tissue thickness on endodontic K-file will be measured using digital vernier caliper. 2. WIDTH OF KERATINIZED TISSUE will be measured using UNC 15 periodontal probe, using a standardized acrylic stent. 3. RADIOGRAPHIC PARAMETERS Crestal bone levels will be measured with CBCT using acrylic stent with gutta percha point for standardization before implant placement (baseline) and after 3 months postoperatively.Timepoint: Baseline to 3 months

—

Secondary

Measure	Time frame
1. Implant Stability Quotient (ISQ) : ISQ will be measured using RFA (Penguin®) immediately after implant placement and at 3 months after implant placement. 2. PLAQUE INDEX (Turskey – Gilmore - Glickman modification of Quigely - Hein Plaque index in 1970) 3. GINGIVAL INDEX (Loe and Silness in 1963)Timepoint: Baseline to 3 months	—

Countries

India

Contacts

Public ContactDr Raagul S

ITS CDSR

dr.rahulchopra@its.edu.in9953865327

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026