Health Condition 1: I830- Varicose veins of lower extremities with ulcer
Conditions
Interventions
Intervention1: Amnion sheet application: Amnion is obtained from the placenta of voluntary donors, after careful screening. The amnion sheets are then treated with antibiotics and preserved. These pro
Sponsors
DR MOHIT NAREN KONDAPALLI
Eligibility
Inclusion criteria
Inclusion criteria: Patients with chronic wounds, such as diabetic foot ulcers, venous ulcers, pressure ulcers, or other non-healing wounds persisting for at least four weeks despite standard wound care. Wounds located on anatomical sites amenable to the application of amnion Patients with chronic wounds without clinical signs of infection or systemic infection at the time of enrolment Patients with a history of standard wound care treatments, including debridement, offloading, and appropriate wound dressings, but no recent use of advanced wound therapies such as growth factors or cellular therapies Patients with stable medical conditions and no acute systemic illnesses that may interfere with wound healing or study participation
Exclusion criteria
Exclusion criteria: Patients with Acute Wounds / Acute Infections Patients with Terminal illnesses / Non-compliant patients Patients with a history of Prior Radiation Therapy Pregnant Patients / Immunocompromised patients Patients with arterial insufficiency as confirmed by ABI & TCPO2 Patients with Uncontrolled Diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound closure rates Timepoint: 6-8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain reduction Improvements to quality of life Cost-effectiveness analysisTimepoint: 8-12 weeks | — |
Countries
India
Contacts
Public ContactMohit Naren Kondapalli
MS RAMAIAH MEDICAL COLLEGE & HOSPITAL
Outcome results
None listed