A study involving comparison of cefazolin alone versus azithromycin plus cefazolin in preventing surgical site infections in patients undergoing cesarean section

Single dose cefazolin versus azithromycin plus cefazolin prophylaxis in preventing surgical site infection in patients undergoing cesarean section: A single blind randomised clinical trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078660

Enrollment

176

Registered

2024-12-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O900- Disruption of cesarean delivery wound

Interventions

Intervention1: Group A - Receiving only cefazolin: Inj cefazolin 1 gm iv,30 mins prior to skin incision of cesarean section Intervention2: Group B - Receiving Azithromycin and cefazolin both: Inj cefa

Eligibility

Inclusion criteria

Inclusion criteria: Singleton and multiple pregnant women who will undergo emergency or elective cesarean section after taking their consent will be included in the study.

Exclusion criteria

Exclusion criteria: Vertical Incision Hypersensitivity history for azithromycin or cefazolin. Azithromycin use in past 7 days before randomisation. Intrauterine death/Fetal Death

Design outcomes

Primary

Measure	Time frame
To compare the efficiency of azithromycin plus cefazolin versus only single dose cefazolin in preventing surgical site infection in patients undergoing cesarean section Timepoint: To compare the efficiency of azithromycin plus cefazolin versus only single dose cefazolin in preventing surgical site infection in patients undergoing cesarean section	—

Secondary

Measure	Time frame
To assess the microbiological pattern in causing surgical site infections in both groups. To study the duration of hospital stay of patients who received cefazolin plus azithromycin as compared to the patients who received only single dose cefazolin. Timepoint: To compare the efficiency of azithromycin plus cefazolin versus only single dose cefazolin in preventing surgical site infection in patients undergoing cesarean section	—

Measure

Time frame

To assess the microbiological pattern in causing surgical site infections in both groups. To study the duration of hospital stay of patients who received cefazolin plus azithromycin as compared to the patients who received only single dose cefazolin. Timepoint: To compare the efficiency of azithromycin plus cefazolin versus only single dose cefazolin in preventing surgical site infection in patients undergoing cesarean section

—

Countries

India

Contacts

Public ContactDr Lajya Devi Goyal

All India Institue of Medical Sciences ,Bathinda

lajja.goyal@rediffmail.com9417658846

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026