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Analgesic Efficacy of Preemptive Ultrasound Guided Transversus Abdominis Plane Block versus Preemptive Subcutaneous Infiltration of incision site in abdominal surgeries

Comparison of Analgesic Efficacy of Preemptive Ultrasound Guided Transversus Abdominis Plane Block and Preemptive Subcutaneous Infiltration of incision site in abdominal surgeries(below T8 level):A Prospective randomised comparative study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078644
Enrollment
60
Registered
2024-12-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pre-incisional Ultrasound guided Transversus Abdominis Plane block 0.5% Bupivacaine with Dexmedtomidine: Transversus abdominis plane block with 0.5% Bupivacaine (2mg/kg) with Dexmeditom

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients of either sex, with ASA physical status grade I, II and III. -Patients scheduled to undergo abdominal surgeries with incisions from or below T8 dermatomal level

Exclusion criteria

Exclusion criteria: 1.Patients who are not willing to participate in the study. 2.Patients with history of hypersensitivity to study drugs. 3.Patients with morbid obesity (BMI more than 35 kg/m2). 4.Patients with previous abdominal surgeries. 5.Patients with hepatic, renal, cardiac and seizure disorders. 6.Pregnant and lactating women. 7.Patients who cannot understand or interpret VAS for pain assessment. 8.Patients who could not be extubated on table.

Design outcomes

Primary

MeasureTime frame
To compare the total morphine consumption in both groups in the first 24hours following surgeryTimepoint: Total morphine dosage requirement according to VAS score will be noted as per patient requirement within 24 hours of post operative period

Secondary

MeasureTime frame
1.To determine the effect of preemptive analgesia on the hemodynamic response to surgical incision in both groups 2.To assess magnitude of pain by Visual analogue scale at different time points 3.To assess the time for first request of rescue analgesia 4.To assess the time after which patient can do deep breathing exercises with the help of incentive spirometry 5.To assess the overall patients satisfaction score by Visual analogue scale at the time of discharge from Post anaesthesia care unit. Timepoint: 1. Hemodynamic response (HR, SBP, DBP, MAP) pre incision(T0), Immediately after surgical incision T1 & at 1min(T2), 2min(T3), 3min(T4) after surgical incision. 2. VAS score 0,15,30,45 minutes & 1,2,4,6,24 hours after surgery 3. The time at which first request of rescue analgesia is noted in post operative period 4. Time after which patient can do incentive spirometry is noted 5. overall patients satisfaction score noted by Visual analogue scale at the time of discharge from PACU.

Countries

India

Contacts

Public ContactDr Peyyety Janaki Subhadra

Sri Venkateshwara Institute of Medical Sciences

subhadrapeyyety@gmail.com9493547655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026