Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified
Conditions
Interventions
Control Intervention1: Nil: Nil
Sponsors
Shama Prasada Kabekodu
Eligibility
Inclusion criteria
Inclusion criteria: Patient undergoing curative image guided radiation with or without chemotherapy Histologically confirmed diagnosis of cervical cancer FIGO stages IB3- IVA
Exclusion criteria
Exclusion criteria: Patients undergoing surgery as the definitive treatment Synchronous carcinomas Metastatic at presentation Poor PS ECOG 3-4 Palliative intent of treatment Prior history of surgery/radiotherapy/chemotherapy to pelvis Neuroendocrine carcinoma of cervix
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To correlate the miRNA level in blood with clinical-radiological response at three months post chemoradiationTimepoint: 3 months after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the miRNA level in blood with 2-year overall survival (OS) and disease-free survival (DFS). To correlate the miRNA level in blood with acute and late toxicities. To assess the quality of life (QOL) of patients undergoing image-guided radiotherapy. To establish patient-derived cell lines for in-vitro functional studies.Timepoint: 2 years post treatment | — |
Countries
India
Contacts
Public ContactShirley Lewis Salins
Kasturba Medical College, Manipal
Outcome results
None listed