Comparative Efficacy of Retrograde Intrarenal Surgery versus Supine Percutaneous Nephrolithotomy for 1–2 cm Kidney Stones

Comparative analysis of Efficacy of Retrograde Intrarenal Surgery (RIRS) versus Supine Percutaneous Nephrolithotomy (PCNL) for Renal Pelvic Stone 1-2 cm: Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078523

Enrollment

Registered

2024-12-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N200- Calculus of kidney

Interventions

Intervention1: Retrograde Intrarenal Surgery (RIRS): Retrograde Intrarenal Surgery (RIRS) is a minimally invasive procedure to remove kidney stones using a flexible fiberoptic endoscope and laser.In p

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with symptomatic renal stones (causing pain, bleeding, or obstruction) confirmed by imaging (CT scan, ultrasound) 2.Stone size 1-2 cm in diameter on largest dimension 3.Age 18 years or older 4.Able to provide informed consent and willing to undergo randomization

Exclusion criteria

Exclusion criteria: 1.Pregnancy 2.Active uncontrolled bleeding disorder 3.Uncontrolled systemic infection/urinary tract infection 4.Previous open renal surgery on the affected kidney 5.Physical attributes that significantly hinder access during RIRS or PCNL (e.g., severe ureteral angulation) 6.Inability to tolerate general anaesthesia (for Supine PCNL)

Design outcomes

Primary

Measure	Time frame
To compare the stone-free rates of retrograde intrarenal surgery versus supine PCNLTimepoint: 1 month	—

Secondary

Measure	Time frame
1.Average duration each surgery. 2.Fall in haematocrit. 3.VAS for pain. 4.Hospital Stay 5.Complication grading according to Clavien Dindo classification.Timepoint: post operative day 1, Post operative at the time of dischage	—

Countries

India

Contacts

Public ContactDr Arvind Kumar

AIIMS Patna

drkamleshg@aiimspatna.org8130412247

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026