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An observational study to predict postoperative complications in liver transplant recipients by applying non-invasive NIRS electrodes over forehead and limbs intraoperatively to observe Cerebral and Somatic Oxygen Saturation, and compare them.

Intraoperative Cerebral and Somatic Oxygen Saturation Monitoring as Predictors of Postoperative Complications in Liver transplantation : An observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/12/078465
Enrollment
50
Registered
2024-12-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K740- Hepatic fibrosis

Interventions

Intervention1: NIL: NIL Control Intervention1: NIRS electrodes will be applied over forehead, forearm and thigh: Fall in oxygen saturation will be compared in cerebral (forehead) and somatic (forearm

Sponsors

Institue of Liver and Biliary Sciences.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cirrhotic patients, Living donor liver transplantation

Exclusion criteria

Exclusion criteria: Acute Liver Failure. Preoperative Hepatorenal Syndrome or Acute Kindney Injury. Pre-existing Chronic Renal Failure. Redo Transplant surgery for graft failure. Diseased Donor Liver Transplantation. Patient refusal.

Design outcomes

Primary

MeasureTime frame
To compare Cerebral and Somatic (either arm or thigh) oxygen desaturation using NIRS during Liver transplant surgery to predict postoperative complications.Timepoint: From start of surgery to postoperative day 7.—

Secondary

MeasureTime frame
Incidence of AKI and associated risk factors. Correlating intraoperative cerebral and somatic oxygen desaturation with postoperative Sr. Creatinine, Sr. Cystatin C and Urine (Neutrophil Gelatinase Associated Lipocalin)NGAL levels. Correlating intraoperative cerebral and somatic oxygen desaturation with postoperative Doppler derived Renal resistive index. Correlating intraoperative cerebral and somatic (arm and thigh) oxygen desaturation for predicting postoperative cognitive dysfunction and Delirium. Correlating intraoperative cerebral and somatic (arm and thigh) oxygen desaturation for predicting postoperative Respiratory complications. Correlating intraoperative cerebral and somatic (arm and thigh) oxygen desaturation for predicting postoperative Cardiovascular complications.Timepoint: From start of surgery to postoperative day 7.—

Countries

India

Contacts

Public ContactDr Udit Dhingra

Institute of Liver and Biliary Sciences, New Delhi

uddh1989@gmail.com8861987684

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026