checking the level of bone growth with and without application of vitamin c mixed with bone graft around teeth with bone loss

Clinical and radiographic evaluation of periodontal bony defect fill with and without ascorbic acid admixed nanohydroxyapatite bone graft. - Nil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078436

Enrollment

Registered

2024-12-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 0.2%mM ascorbic acid gel admixed nanohydroxyapatite bone graft: open flap debridement will be done in target site and ascorbic acid admixed nanahydroxyapatite bonegraft is placed into i

Eligibility

Inclusion criteria

Inclusion criteria: Who are systemically healthy Both males and females with age =30 years having periodontitis with bilateral bony defects. Pocket depths =5 mm after phase 1 evaluation. Radiographic evidence of bone loss. Participants who are co-operative and able to come for regular follow-up. Participants with =20 remaining teeth

Exclusion criteria

Exclusion criteria: Pregnant/lactating women Individuals who are known allergic to ascorbic acid. Who received antibiotic therapy in the previous 6 months Who underwent periodontal therapy in the past 6 months Use of tobacco in any form Medically compromised or under therapeutic regimen that may alter the probability of periodontal healing

Design outcomes

Primary

Measure	Time frame
Periodontal probing depths(PD) Clinical attachment levels(CAL) amount of bone fill Amount of bone fill Timepoint: baseline,one month,6 months & 9 months	—

Secondary

Measure	Time frame
Gingival Bleeding Index Percentage Of BonefillTimepoint: Baseline,one months,six months,9 months	—

Countries

India

Contacts

Public ContactDr Sumanth Gunupati

Narayana Dental College And HOSPITAL,NELLORE

sumant29@gmail.com9848385378

Outcome results