A comparative study between two doses of dexmedetomidine 0.5µg/KG and 1µG/kg as an adjuvant to 0.25% ropivacaine in adductor canal block for management of post operative pain in knee surgeries under spinal anaesthesia

A comparative study of efficacy and safety of two different doses of dexmedetomidine – 0.5µg/Kg and 1µg/Kg as an adjuvant to 0.25% ropivacaine in ultrasound guided adductor canal block for postoperative analgesia in knee surgeries under spinal anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078422

Enrollment

Registered

2024-12-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified

Interventions

Intervention1: Group RD. Adductor canal block using 0.25% ropivacaine with 0.5µg/kg as an adjuvant.: Patient in supine position with thigh abducted and externally rotated to allow access to medial thi

Eligibility

Inclusion criteria

Inclusion criteria: posted for elective knee surgeries under spinal anaesthesia ASA grade II and II

Exclusion criteria

Exclusion criteria: Allergy to drugs used in study Patients having contraindications to adductor canal blocks(local site infections, coagulopathies) Known neurological deficits

Design outcomes

Primary

Measure	Time frame
1. To assess and compare postoperative analgesia using the numerical pain rating scale 2. To assess and compare number of rescue analgesics required within 24hrsTimepoint: 0 MIN (MOMENT BLOCK IS GIVEN) 30 MIN 60 MIN 90 MIN 120 MIN 6 HOURS 12 HOURS 18 HOURS 24 HOURS	—

Secondary

Measure	Time frame
1. To assess and compare motor blockade between two groups using modified bromage scale 2. To assess and compare haemodynamic parameters 3. To assess and compare sedation score between two groups 4. any adverse effects during first 24 hours post surgeryTimepoint: 0 MIN (MOMENT BLOCK IS GIVEN) 30 MIN 60 MIN 90 MIN 120 MIN 6 HOURS 12 HOURS 18 HOURS 24 HOURS	—

Countries

India

Contacts

Public ContactDr. Pramod Bhale

MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES, AURANGABAD

pramod.bhale@gmail.com8888819021

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026