Health Condition 1: G64- Other disorders of peripheral nervous system Health Condition 2: G64- Other disorders of peripheral nervous system
Conditions
Interventions
Intervention1: Opioid Based group receive intravenous fentanyl: Administration of fentanyl bolus 2mcg/kg bolus 3 minute prior to induction of anaesthesia followed by infusion fentanyl 0.5 mcg/kg/hour
Sponsors
Dr SN Medical College jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: • The Patients of age =18-70 yrs of either gender of ASA category 1,2 and 3 undergoing major spine surgery under general anaesthesia who are haemodynamically stable and declared fit in pre- anaesthetics checkup.
Exclusion criteria
Exclusion criteria: Patient refusal, Patient having known history to allergy to dexmedetomidine, lignocaine and fentanyl and other anaesthetic drugs, patient with history of substance abuse, patient psychiatric illness, cardiac and hepatic insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the total dose of rescue analgesic requirement up to 48 hours post operatively after major spine surgery.Timepoint: To compare the total dose of rescue analgesic requirement up to 48hours post operatively. From the time patient wakes up from anesthesia to 48 hours post operatively. When VAS is more than 4 | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity by visual analogue score in both the groups. Hemodynamic stability and respiratory parameters (SBP, DBP, MAP, HR, SPO2). The length of post operative hospital stays in both the groups. The side effects such as nausea, vomiting, and respiratory depression, pruritus etc. Post anaesthesia discharge scores according to modified aldrete score. Timepoint: Modified aldrete score will be noted before discharge from post anaesthesia care unit.if score more than and equal to 9 patients will be dicharege. Haemodynamics and respiratory parameters and VAS will be noted on arrival in operation theater than every 15 minutes in intraoperative periods than every hourly upto 6 hours than every 4 hourly upto 24 hours than 6 hourly upto 48 hours. If any side effects and total duration of hospital stay will be also noted. | — |
Countries
India
Contacts
Public ContactDr.Bhagyashree
Dr S N Medical college jodhpur
Outcome results
None listed