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Incidence of Haemolysis during Cardiopulmonary Bypass on Adult Cardiac Surgeries

A Pilot Randomized Controlled Trial on Incidence of Haemolysis during Cardiopulmonary Bypass on Adult Cardiac Surgeries - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078407
Enrollment
30
Registered
2024-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I20-I25- Ischemic heart diseases Health Condition 2: I71- Aortic aneurysm and dissection

Interventions

Intervention1: Interventional Group: 1. Meniscus fall method (1 inch/ min) 2. Vacuum Assisted Venous Drainage Pressures -20mmHg to -40mmHg 3. Sucker range less than 0.65 lpm during the intra OP 4. D

Sponsors

D E Nirman Kanna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult Cardiac surgeries which require the use of cardiopulmonary bypass and CPB time more than 60mins.

Exclusion criteria

Exclusion criteria: 1. Patients with renal impairments 2. Patients with hemolytic disorders 3. Patients with pre-existing hemolysis 4. Patients with cyanotic heart disease 5. Cardiac surgeries with CPB duration exceeding 240 minutes 6. Cardiac surgeries using non-occlusive pumps 7. Cases requiring a return to CPB 8. Redo surgeries (especially Mechanical valve implanted cases) 9. Emergency CPB initiation 10. Patients unwilling to participate in the study

Design outcomes

Primary

MeasureTime frame
Incidence of HemolysisTimepoint: Itra Operative (60mins after CPB ON) and Post Operative period (12hrs after CPB OFF) POD 0—

Secondary

MeasureTime frame
To delineate the risk factors that increase the incidence of hemolysisTimepoint: Itra Operative (60mins after CPB ON) & Post Operative period (12hrs after CPB OFF) POD 0—

Countries

India

Contacts

Public ContactDr Varun Shetty

Narayana Institute of Cardiac Sciences

varun.shetty.dr@narayanahealth.org9880933801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026