Comparision of outcomes between two types of omentum removal during surgery in ovarian cancer patients

Perioperative Outcomes in Total infragastric Omentectomy with or without Perigastric Arcade Resection in advanced epithelial OVarian cancer: A non-inferiority randomized-controlled-trial(POTOPAR-OV) - POTOPAR-OV

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078395

Enrollment

104

Registered

2024-12-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C569- Malignant neoplasm of unspecifiedovary Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Group 2 (Omentectomy including perigastric arcade): Patients in intervention arm are in whom total infragastric omentectomy done including the perigastric arcade after ligating right an

Eligibility

Inclusion criteria

Inclusion criteria: Stage III or IV epithelial ovarian cancer patients undergoing primary cytoreductive or interval cytoreductive surgery

Exclusion criteria

Exclusion criteria: Gross disease present in perigastric arcade part of omentum during intraoperative assessment. Previous gastric surgery Recurrent ovarian cancer

Design outcomes

Primary

Measure	Time frame
To compare perioperative complication rates between total infragastric omentectomy with or without perigastric arcade resection during cytoreductive surgery in advanced epithelial ovarian cancerTimepoint: one week post surgery	—

Secondary

Measure	Time frame
To compare patients quality of life after 30 days of surgery among the perigastric arcade removal and perigastric arcade preserving groups based on EORTC QLQ-OV28 questionnaire.Timepoint: 1 month post surgery;To compare the disease-free survival in both perigastric arcade removal and perigastric arcade preserving groups after 6 months of surgery.Timepoint: six months post surgery;To assess the rate of microscopic involvement of the perigastric arcade of the omentum in patients undergoing total infragastric omentectomy with perigastric arcade resection & their predictive factors.Timepoint: Two weeks post surgery;To compare other perioperative outcomes between two arms including intraoperative blood loss, operative time, intensive care unit (ICU) admission rates & length of hospital stay (days).Timepoint: one week post surgery	—

Measure

Time frame

To compare patients quality of life after 30 days of surgery among the perigastric arcade removal and perigastric arcade preserving groups based on EORTC QLQ-OV28 questionnaire.Timepoint: 1 month post surgery;To compare the disease-free survival in both perigastric arcade removal and perigastric arcade preserving groups after 6 months of surgery.Timepoint: six months post surgery;To assess the rate of microscopic involvement of the perigastric arcade of the omentum in patients undergoing total infragastric omentectomy with perigastric arcade resection & their predictive factors.Timepoint: Two weeks post surgery;To compare other perioperative outcomes between two arms including intraoperative blood loss, operative time, intensive care unit (ICU) admission rates & length of hospital stay (days).Timepoint: one week post surgery

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Countries

India

Contacts

Public ContactDr Jeewan Ram Vishnoi

All India Institute Of Medical Sciences- Jodhpur

drjvishnoi@gmail.com9455061569

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026