A comparison of two spinal anaesthesia drugs Levobupivacaine 0.5 percent and Ropivacaine 0.75 percent combined with Buprenorphine in patients undergoing surgeries on the lower abdomen and legs

Comparative study of Intrathecal Hyperbaric Levobupivacaine 0.5 percent and Hyperbaric Ropivacaine 0.75 percent with Buprenorphine in patients undergoing lower abdominal and lower limb procedures under subarachnoid block. A prospective randomised double blind study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078362

Enrollment

Registered

2024-12-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Levobupivacaine with Buprenorphine: Intrathecal Levobupivacaine 0.5% heavy with Buprenorphine 60mcg to assess onset and duration of sensory and motor blockade in patients undergoing low

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists (ASA) grade I-III. 2. Age group between 18-60 years of both sexes. 3. Scheduled for Elective and emergency lower abdominal and lower limb surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. History of allergy to study drugs 3. Post spinal surgeries, Spinal Deformities, skin sepsis in lumbar region, patients with pre-existing neurological disorders. 4. Coagulopathy, Dysrhythmia 5. Major Hepatic, Renal and Cardiovascular Dysfunction 6. BMI more than 35, Height less than 140cms 7. Surgeries involving major blood loss

Design outcomes

Primary

Measure	Time frame
1.To compare onset and duration of sensory and motor blockade. 2.To assess and compare the haemodynamic parameters between both groups. Timepoint: First 5 hours	—

Secondary

Measure	Time frame
1.To assess two segment sensory regression time 2.Side effect if any Timepoint: First 5 hours	—

Countries

India

Contacts

Public ContactS VAISHNAVI

CHETTINAD HOSPITAL AND RESEARCH INSTITUTE

ashokk_dr@yahoo.com9840498420

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026