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Comparison the effect of dexmedetomidine and magnesium sulphate in controlled hypotension during functional endoscopic sinus surgery

Comparison the effect of dexmedetomidine and magnesium sulphate in controlled hypotension during functional endoscopic sinus surgery - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/12/078351
Enrollment
70
Registered
2024-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Administer a loading dose of 1 mcg/kg of dexmedetomidine over 10 minutes, followed by a continuous infusion at a rate of 0.5 mcg/kg per hour until the end of the surger

Sponsors

Dr Sandeep Kumar Dwivedi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group between 18-60 years 2.ASA grade I and II 3.Patients will be scheduled to undergo FEES under GA

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Effect of Study Drugs on Hemodynamic Parameters Metric: Change in mean arterial pressure (MAP) and heart rate from baseline.Timepoint: Effect of Study Drugs on Hemodynamic Parameters Metric: Change in mean arterial pressure (MAP) and heart rate from baseline.

Secondary

MeasureTime frame
Assessment of Bleeding Grade Metric: Bleeding graded on a standardized scale (e.g., minimal, moderate, or severe)Timepoint: Throughout the surgical procedure; 2. Surgeon’s Satisfaction Metric: Satisfaction score (scale: 1–10) based on surgical conditions and bleeding control:Timepoint: Postoperative feedback collected within 1 hour of surgery completion; 3. Recovery from Anesthesia Metric: Aldrete score (=9 for full recovery)Timepoint: Assessed at 15-minute intervals until discharge from the post-anesthesia care unit; 4. Sedation Evaluation Metric: Ramsay sedation score (1–6 scale)Timepoint: Timepoint: Measured at 10, 20, and 30 minutes after administration of the study drug; 5. Untoward Effects of Study Drugs Metric: Frequency and type of adverse effects observed (e.g., nausea, vomiting, allergic reactions) Timepoint: Timepoint: Monitored during surgery and within 24 hours postoperatively

Countries

India

Contacts

Public ContactDr Sandeep Kumar Dwivedi

Gajra Raja Medical college

drssy_17@yahoo.com9826284553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026