Study comparing Dexmedetomidine, clonidine, and Pethidine to prevent shivering after spinal anesthesia in surgery

A randomised double blinded study of Dexmedetomidine, clonidine,pethidine for control of post spinal shivering in patients undergoing elective surgeries - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078347

Enrollment

Registered

2024-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Dexmedetomidine and clonidine: Dexmedetomidine 0.5 mcg/ kg intravenous dose and clonidine 1 mcg/kg intravenous dose will be given when shivering occurs after spinal anesthesia for 2 hrs

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1)Patients aged 20-60 years 2)ASA -1,2 3)Shivering grade 2-3 ( Crossley and Mahajan scale) 4)Elective surgeries

Exclusion criteria

Exclusion criteria: 1) patient aged less than 20 yrs and more than 60 yrs 2)Fever, drug allergic reactions ,thyroid illness, neuromuscular diseases 3)Patients with cardiac disease( heart blocks,LVF) ,psychiatry illness 4)Patient who develop shivering even before giving spinal Anesthesia ASA -3,4

Design outcomes

Primary

Measure	Time frame
To compare the time taken to control shivering between Dexmedetomidine, clonidine , pethidineTimepoint: 120 mins	—

Secondary

Measure	Time frame
To assess sedation using Filos sedation scale To assess other hemodynamic changes , adverse effects of these drugsTimepoint: 120 mins	—

Countries

India

Contacts

Public ContactDr ASHOK KULASEKHAR

Chettinad Hospital and research Institute

ashokk_dr@yahoo.com9840498420

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026