Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: PET-G formed oral tissues repositioning stent: The designed intraoral repositioning stent made from vacuum-formed PET-G sheets, with a thickness of 3mm, will be used during every sessio
Sponsors
AIIMS Mangalagiri
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Oral Cavity, Oropharyngeal, Nasopharyngeal and Maxillary Sinus cancers Exposed to the same radiation field and radiation source and dosages between 60 and 70 Gy Mouth opening allowing to take dental impressions The patient should be able to provide a salivary sample Dental condition enabling adequate stent retention
Exclusion criteria
Exclusion criteria: Local extension of carcinomatous tissue which will interfere with appliance fabrication or cause trauma Active intraoral infection Recurrence of carcinomas Previous history of radiation for treatment of cancers Cases with resected salivary glands.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dose sparing effect as measured by dose volume histogram, accuracy of patient positioning progression of muscositisTimepoint: Dose sparing effect as measured by dose volume histogram, accuracy of patient positioning will be evaluated during all radiotherapy sessions. Baseline data will be collecetd at time point zero for mucocitis, salivary flow and mouth opening. Mucocitis will be evaluated weekly at week 1, week 2 , week 3 and week 4. Mouth opening at salivary flow will be evaluated after 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| progression of muscositis, reduction in salivary flow (xerostomia) and reduction in mouth openingTimepoint: 1 month and 3 months | — |
Countries
India
Contacts
Public ContactDr. Jitendra Chawla
All India Institute Of Medical Sciences, Mangalagiri
Outcome results
None listed