Comparison of muscle recovery after giving two drugs sugammadex versus neostigmine in obese patients undergoing laparoscopic gynaecological surgeries

Comparison between sugammadex and neostigmine in terms of postoperative respiratory muscle strength recovery in obese patients undergoing laparoscopic gynaecological surgery. A randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078308

Enrollment

Registered

2024-12-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Sugammadex as reversal agent: Sonographic assessments : Lung, Diaphragm and respiratory muscle thickness ultrasonography will be performed by using 2-5 MHZ transducers. Images will be o

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 years with BMI greater than 30kg/m2 undergoing laparoscopic gynaecological surgeries

Exclusion criteria

Exclusion criteria: 1. Significant kidney disease (stage 4 kidney disease or higher). 2.Significant liver disease (Child Pugh B or C class) 3. Allergic to neostigmine or sugammadex. 4. Any history of a neuromuscular disorder. 5. History of chronic obstructive pulmonary disease. 6.Pregnancy or nursing women.

Design outcomes

Primary

Measure	Time frame
To assess the recovery of respiratory muscle strength using thickening fraction of internal obliqueTimepoint: calculated at 30 minutes and 120 minutes after giving reversal agent and compare with baseline values	—

Secondary

Measure	Time frame
To assess the post operative atelectasis by the modified LUS score based on lung ultrasound. To assess the recovery of diaphragm, by assessing diaphragm excursionTimepoint: calculated at 30 minutes and 120 minutes after giving reversal agent and compare with baseline values	—

Countries

India

Contacts

Public ContactDr Rajnish Kumar

AIIMS PATNA

Drraj76pmch@gmail.com7783865337

Outcome results