Health Condition 1: C67- Malignant neoplasm of bladder Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Omission of restage TURBT: The process of randomization will begin once histopathology report of the primary TUR is obtained. No re-TUR arm:
1. Patients with TaHG/T1LG histopathologie
Sponsors
AIIMS, NEW DELHI
Eligibility
Inclusion criteria
Inclusion criteria: Primary presentation bladder cancer without any prior resection or intravesical treatment Patients with HPE report of LG, T1 or HG, Ta with presence of detrusor muscle in the specimen Tumour size less than 3cm Tumours less than 3 in number Patients with HPE report of HG T1 with a single tumour less than 3cm in size operated by faculty with presence of detrusor muscle in the specimen Aged more than 18 years Written informed consent
Exclusion criteria
Exclusion criteria: Patients who have undergone TURBT for bladder cancer with a postop HPE report of HG T2 Patients with history of previous TURBT CIS Tumour size more than 3cm Multiple tumours more than 3 in number Patients with a postop HPE report of HGT1 with tumour size more than 3cm or more than 1 tumour Absence of detrusor muscle in the specimen Incomplete resection of tumour Variant histology Patients who do not give informed consent. Perforation during initial TURBT American Society of Anesthesiologists Score more than 3
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of recurrence in patients who undergo reTUR vs those who do not undergo reTUR Incidence of progression in patients who undergo reTUR vs those who do not undergo reTUR Tumor upstaging in patients who undergo a reTUR. Timepoint: Followup at 3 months, 6 months, 9 months and 1 year after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to recurrence & progression between the two groups Time to delay in definitive treatment in patients who undergo a reTUR Timepoint: Followup of 3 months, 6 months, 9 months & 1 year after surgery | — |
Countries
India
Contacts
Public ContactMOUNIKA BALABOLU
All India Institute of Medical Sciences , New Delhi
Outcome results
None listed