Health Condition 1: I229- Subsequent ST elevation (STEMI) myocardial infarction of unspecified site
Conditions
Interventions
Intervention1: Inhalational agent Sevoflurane: Effect of inhalational agent sevoflurane on left ventricular diastolic function in patients undergoing CABG using cardiopulmonary bypass
Control Interven
Sponsors
Muthu M
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients undergoing elective coronary artery bypass graft surgery using cardiopulmonary bypass.
Exclusion criteria
Exclusion criteria: Decreased Left ventricular ejection fraction ,Cardiomyopathy,Pre existing valvular heart disease,Pre existing diastolic dysfunction, Atrial fibrillation, Significant pulmonary diseases, Emergency procedure, Oesophageal pathology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate left ventricular diastolic function by measuring Peak flow velocity of early diastolic filling/ Early diastolic mitral annulus velocity using Transesophageal echocardiography under sevoflurane or propofol based anaesthesia in patients undergoing Coronary artery bypass graft on cardiopulmonary bypassTimepoint: After intubation and after weaning from cardiopulmonary bypass | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare other parameters of diastolic and systolic function between sevoflurane and propofol group that is Late diastolic filling, Deceleration time, Peak systolic flow velocity, Peak diastolic flow velocity, S/D ratio, Peak reversal atrial flow, Duration of reverse atrial flow, Left Ventricular Ejection Fraction. To determine the Vasoactive inotropic Score between sevoflurane group and propofol group. To assess the duration of Mechanical ventilation and ICU stay between sevoflurane group and propofol group Timepoint: after intubation and after weaning from cardiopulmonary bypass | — |
Countries
India
Contacts
Public ContactDr Nihar Ameta
Armed forces medical college
Outcome results
None listed