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To compare the effect of Erector spinae block on IL-1 beta IL-6 and TNF-alpha and serum cortisol in traumatic spine surgeries

The effect of erector spinae block on inflammatory mediators and stress hormone in traumatic spine surgeries Randomised prospective control trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078214
Enrollment
28
Registered
2024-12-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S249- Injury of unspecified nerve of thorax Health Condition 2: S341- Other and unspecified injury of lumbar and sacral spinal cord

Interventions

Intervention1: Erector spinae block: To the patients in trial group E bilateral Erector spinae block will be given under ultrasound guidance with 20mL 0.2 percent Ropivacaine Control Intervention1: No

Sponsors

Department of Anaesthesiology Institue of Medical sciences Banaras Hindu University Varanasi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Includes those undergoing traumatic Thoracolumbar spine surgeries belonging to American society of anaesthesiologists physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal Age more than 60 or less than 18 Patient with uncontrolled hypertension diabetes mellitus immunological disorders Patients having allergy to any of the drugs administered Obesity with BMI more than 30 kg per metre squared

Design outcomes

Primary

MeasureTime frame
Effect of Erector spinae block on inflammatory mediators IL-1beta, IL-6 and TNF-alpha and serum cortisol levelsTimepoint: Parameters to be checked immediately post extubation, after 24 hours, 48 hours post surgery

Secondary

MeasureTime frame
Effect of Erector spinae block on perioperative hemodynamics & post operative pain-VAS scoreTimepoint: Perioperative hemodynamics -baseline, After 15 minutes 30 minutes, 45 minutes, 60 minutes, 75 minutes VAS SCORE- 1 Hour, 2 Hours, 4 Hours, 6 Hours, 8 Hours, 12 Hours, 24 Hours

Countries

India

Contacts

Public ContactSumita Kumari

Banaras Hindu University

uanand425@gmail.com8789172374

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026