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Comparison of efficacy of topical Trifarotene and Tretinoin in acne vulgaris

Comparitive efficacy of topical Trifarotene and Tretinoin in acne vulgaris - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078197
Enrollment
50
Registered
2024-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Trifarotene 0.005 percent cream: Patient will be asked to apply topical trifarotene 0.005 percent cream local application over the affected areas of the face at bedtime for a total dura

Sponsors

Government Medical College and Hospital Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of acne vulgaris (grade 1 & 2)involving face and not requiring systemic therapy 2.Patients of 16-50 years of age.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating mothers 2.Patients with severe systemic illness requiring systemic therapy of more than 4 weeks 3.Patients with signs and symptoms of hyperandrogenism 4.Patients with truncal acne

Design outcomes

Primary

MeasureTime frame
1.Percentage improvement and reduction in the total lesion count from the baseline 2.Reduction in total lesion count assessed through clinical photographyTimepoint: At Baseline,3 weeks,6 weeks,9 weeks and 12 weeks.

Secondary

MeasureTime frame
1.Patient-reported outcomes: Evaluation of treatment satisfaction & improvement in acne. 2.Adverse effects: Monitoring & categorization of adverse events related to each treatment using the Numeric Rating Scale . Timepoint: At baseline,3 weeks,6 weeks,9 weeks & 12 weeks.

Countries

India

Contacts

Public ContactDr. Mala Bhalla

Government Medical College and Hospital Chandigarh

malabhalla@yahoo.co.in9646121545

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026