Health Condition 1: A270- Leptospirosis icterohemorrhagica Health Condition 2: A279- Leptospirosis, unspecified Health Condition 3: A753- Typhus fever due to Rickettsia tsutsugamushi
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Indian Council of Medical Research (ICMR)
Eligibility
Inclusion criteria
Inclusion criteria: AFI patients positive for leptospirosis and scrub typhus infections by either RDT or IgM ELSA Patients =18 years Patients who are willing to give informed consent
Exclusion criteria
Exclusion criteria: Patients with co-infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development and validation of a clinical scoring system to differentiate leptospirosis and scrub typhus, which might help in the early detection and choosing empirical antibiotics Determination of the prevailing genotypes and serovars and their association with the disease severity among leptospirosis and scrub typhus Understanding the changes in serum & urine metabolites that are associated with these infections Determining a significant metabolite that can be used as a biomarker to distinguish between leptospirosis and scrub typhusTimepoint: 1st week of illness | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: MIL | — |
Countries
India
Contacts
Public ContactDr Kavitha Saravu
Manipal Academy of Higher Education Manipal
Outcome results
None listed