Comparing Pain Relief in Knee Osteoarthritis: Thermal Radiofrequency Ablation with Ultrasound-Guided i-PACK Block Using Classical vs. Revised Targeting Techniques

To compare the effect of thermal radiofrequency ablation of the genicular nerves, along with ultrasound-guided i-PACK block, in providing pain relief in patients with osteoarthritis of the knee joint, using the classical versus revised target technique. - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078158

Enrollment

Registered

2024-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: GROUP II Revised anatomical target approach group (R): A single, experienced interventionist will perform all the interventions as per group assigned on opening the sealed envelopes. Th

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with stage 1, 2 and Stage 3 of Kellgren-Lawrence classification based on X-ray knee joint 2. Criteria age from 40 to 70 years 3. Pain localized to knee joint with no referred pain or any other cause of knee pain 4. Patients without visible gross structural deformity of the knee joint 5. Patients with American Society of Anaesthesiologists Grade I and II 6. patients with Visual Analogue Scale more than 4 7. Patients on conservative treatment such as physical therapy, analgesic drugs including NSAIDs or opioids, for at least six months.

Exclusion criteria

Exclusion criteria: • Patient refusal • Patientâ??s with gross deformity of the knee joint or associated tendon pain and bursitis. • Existence of general contraindications against application of invasive intervention (such as hemorrhagic diathesis, on antiplatelets and anticoagulant therapy, systemic infection, or local infection at the area to be intervened and patient with pacemakers • Psychiatric disorders and drug dependence/abuse • Acute knee pain and prior knee surgeries.

Design outcomes

Primary

Measure	Time frame
1.To compare the effect of thermal Radio frequency of the genicular nerve along with ultrasound guided i-PACK block in providing pain relief in patients of osteoarthritis of the knee joint using classical versus the new revised target techniqueTimepoint: post procedure , 1, 4, 8,12 weeks	—

Secondary

Measure	Time frame
2. To compare the total analgesic intake in both patient groups throughout the observation period.Timepoint: post procedure, 1 , 4, 8, 12 weeks	—

Countries

India

Contacts

Public ContactANUPAM SHARMA

dr Yashwant Singh Paramar Govt medical college Nahan

drsharma3105@gmail.com09418031481

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 9, 2026