Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intramuscularly dexmedetomidine 1.5mcg/kg: Inj. Dexmedetomidine 1.5mcg/kg intramuscular 60 minutes prior to induction of general anaesthesia
Control Intervention1: Intramuscularly dexme
Sponsors
Smt Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to sign informed consent. Male or female patients between 18 to 60 years of age. Patients belonging to American Society of Anesthesiologists (ASA) physical status I and II. Patients posted for elective surgeries under general anaesthesia.
Exclusion criteria
Exclusion criteria: Patients unwilling to participate in the study. Patients with Body Mass Index = 30 kg/m2. Patients with history of muscular disorder , myositis , or any local infection Patients with cardiovascular diseases, arrhythmias, heart blocks, or taking beta blockers. Patients with cerebrovascular, hepatic and renal diseases. Psychiatric patients. Patients with history of allergy to an a-2 adrenergic agonist Pregnancy & lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To check efficacy of dexmedetomidine for blunting hemodynamic response during laryngoscopy and intubation in two different doses via intramuscular route.Timepoint: baseline after test drug administration at 15 minutes, 30 minutes, 45 minutes and one hour after induction at laryngoscopy and intubation 1 min after intubation 3 mins after intubation 5 minutes after intubation 7 minutes after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To study sedation score or any other side effectsTimepoint: post-operatively sedation status will be assessed every 30 minutes by RAMSAY sedation score till a score of less than or equal to 3 will be achieved. | — |
Countries
India
Contacts
Public ContactDr Sara Mary Thomas
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Outcome results
None listed