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A clinical trial to study the effect of 2 drugs(nalbuphine and magnesium sulphate) with levobupivacaine in infra umbilical surgeries

Comparative Study Between Nalbuphine V/S Magnesium Sulphate As An Adjuvant To Intrathecal Hyperbaric Levobupivacaine In Infraumbilical Abdominal Surgeries - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078110
Enrollment
80
Registered
2024-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K469- Unspecified abdominal hernia without obstruction or gangrene

Interventions

Control Intervention1: Levobupivacaine with Magnesium Sulphate or Nalbuphine: Comparison of block characteristics in terms of Time Taken for Onset of Sensory and Motor Block. Duration of Motor Block.

Sponsors

Hind Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA-1 and ASA-2 Age 18yrs to 60 yrs

Exclusion criteria

Exclusion criteria: Patient Refusal Pregnancy Obesity Contra Indication to Spinal Anaesthesia Allergy to Study Drug Patients with Cardiac, Liver and Renal Disease Previous Surgery of Lumbar Spine

Design outcomes

Primary

MeasureTime frame
Comparison of block characteristics in terms of Time taken for onset of sensory and motor blocks. Duration of sensory and motor blocksTimepoint: Assess the heart rate, blood pressure, oxygen saturation and MAP

Secondary

MeasureTime frame
Duration of analgesic effect, Peak VAS pain scores during recovery period, Total amount of rescue analgesia used. Post-operative hemodynamic changes.Timepoint: Assess the VAS Score , Vitals in Post-operative period every 30 mins till 2 hours and every 1 hour till 12 hours, time taken for first rescue Analgesia.

Countries

India

Contacts

Public ContactDrSudhir Kumar Rai

Hind Institute of Medical Sciences

sudhir.rai17@gmail.com9455106967

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026