Health Condition 1: M472- Other spondylosis with radiculopathy
Conditions
Interventions
Intervention1: Dexamethasone 0.2mg/kg, Dexmedetomidine 0.5-0.7 mcg/kg/hr: Intravenous Dexamethasone will be given 1 hour before surgery. Intravenous Dexmedetomidine infusion will be started after pron
Sponsors
All India Institute of Medical Sciences, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients of ASA physical status I and II posted for elective lumbar spine surgery of 1 or 2 levels.
Exclusion criteria
Exclusion criteria: 1. Patients refusal 2. Patients belonging to class: ASA physical status III and IV 3. Limitations in understanding use of PCA pump 4. Patients with a preoperative heart rate less than 60 beats per minute 5. Chronic analgesic or steroid use 6. Presence of significant dysfunction like cardiovascular, neurological, respiratory, hepatic or renal 7. History of uncontrolled diabetes mellitus 8. Patients having history of drug abuse 9. Known allergy to drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total intravenous Patient Controlled Analgesia (PCA) fentanyl consumption 24 hours postoperativeTimepoint: Total intravenous Patient Controlled Analgesia (PCA) fentanyl consumption 24 hours postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for first analgesic requirementTimepoint: 24 hours postoperative;Pain scores at rest and during movement at 0 min, 1 hour, 4 hours, 8 hours, 12 hours, 24 hours postoperativeTimepoint: 0 minute, 1,4,8,12,24 hours postoperative;Postoperative nausea and vomitingTimepoint: 0, 15, 30 minutes, 1,2,4,8,12,24 hours postoperative;Hyperglycaemic state of patient till 24 hours after surgeryTimepoint: 1 hour before surgery, 1 hour after surgery, 8th hourly till 24 hours postoperative;Wound healing/infection at 1 weekTimepoint: 7 days postoperative | — |
Countries
India
Contacts
Public ContactVarshini G
All India Institute of Medical Sciences
Outcome results
None listed